91ֱ��

Christopher Ayoub got his first taste of research in the biology labs of 91ֱ��. By the summer after his sophomore year, he had secured an internship researching circadian rhythms at the University of Texas Health Science Center. The following summer, he was investigating bone formation at Washington University in St. Louis. 

Each time, he returned to 91ֱ�� to push his research further under the guidance of biology professor Maureen Peters. Their work together led directly to Ayoub’s first job after graduation: as a research technician at Baylor College of Medicine. 

Today the 2015 grad from Houston, who completed 91ֱ�� majors in anthropology and biology, is pursuing two more degrees that span both disciplines: a PhD and MD at Ohio State University. 

We caught up with Ayoub to learn more about his journey since 91ֱ��.

You pursued two majors at 91ֱ�� and were a varsity athlete on the swimming and diving team. What was it like balancing all of that?

Balance is the key word. Each one of those gave me a break from the others, such that doing all of those things helped me not to get burned out. I was also in the College Choir, which added a little music to the mix too! 

I actually came to 91ֱ�� with no clue what major I wanted to pursue. I created a giant spreadsheet every time class registration came around because I wanted to make sure I kept my options open. Over the course of several semesters, I realized I loved biology—thank you, [Emeritus Professor] Yolanda Cruz—and I wanted to balance the natural science with a social science. I had narrowed it down to English and anthropology, but Introduction to Linguistic Anthropology with Professor Erika Hoffmann-Dilloway really drew me in—not to mention Human Origins with Professor Amy Margaris, which merged the two subjects! Then there was swimming, which gave me an escape from academics, alternative goals to focus on, exercise for endorphins, and a team that was my family away from home. The was a vital support system for me to maintain my sanity and to find joy at 91ֱ��.

What inspired you to pursue a career in medical research?

As I was figuring out what to do with a biology major or an anthropology major, I knew a lot of peers who had research positions. Molecular biology was particularly captivating to me because many of its techniques, like PCR [polymerase chain reaction] and Western blotting, elegantly take advantage of naturally occurring biological mechanisms. While I was at UT Health, my first research mentor, Dr. Seung-Hee Yoo, was also the first to suggest the double-major pathway to me. 

As this simmered at the back of my mind, I began to think of it as a way to continue both of my majors. There were 13 programs around the country that would allow me to continue anthropology as a PhD and biology as an MD. However, I was doing more biology research at 91ֱ�� with Professor Peters and more the next summer at Washington University, and I realized that I love biology research, which would not be continued through a PhD in anthropology. I also realized that the MD could just as easily be the extension of my anthropology major, as I would be working with patients and other medical professionals from all walks of life. 

With that perspective in mind, I started to see how the two degrees would work together—where medicine informs the gaps in understanding and care that need to be addressed through research, and where research inspires changes that advance the standard of care. Pursuing medicine and research together constantly keeps the other in perspective. For me, it’s very motivating to know that my research has the potential to have a real impact on people’s lives by improving health outcomes. Good health is fundamental to so much of our lives.

What sort of research did you do at 91ֱ��?

In Maureen Peters’ lab, I studied the defecation motor program in C elegans [a type of roundworm], a tightly controlled, repetitive behavior that occurs roughly every 50 seconds. More specifically, I was part of investigating the permissive conditions that allow the expulsion contraction to take place at the end of every 50 seconds. The independence and freedom Professor Peters gave me to follow my observations really allowed me to develop my scientific curiosity. The technical skills she taught me in handling worms also helped me snag my first job after 91ֱ��, where I was a research technician in a C elegans microbiome lab at Baylor College of Medicine.